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Organic Functionalization of Fullerenes


Water soluble Fullerene Derivatives exhibit a number of exciting biological activities that attracted attention of many research groups around the world. Intensive studies resulted in the discovering antiviral, antitumor, antimicrobacterial and antioxigenyc effects of the C60 derivatives.

As a result, the new series of AminoAcids and Peptide Derivatives of C60 possessing well pronounced membranotropic, antioxidant,antiviral and immunomodulating properties was designed.

We offer the sodium salt of Aminocapronic acid (1) and Aminobutyric Acid (2) which are very soluble in the water ( >50mg/ml ) and exhibit a strong anti - HIV and adjuvant activity:
  1. C60(H) NH ( CH2 )5 COO Na
  2. C60(H) NH ( CH2 )3 COO Na
Please contact us regarding of the minimum order, price, delivery terms etc.

Also we can offer the Water soluble C60 Derivatives with many another AminoAcids: Gly, Ala, Ser, Pro, Arg etc.


WATER-SOLUBLE AMINOACIDS DERIVATIVES of C60


1.“Fullerene-Derivatized Amino Acids:Synthesis,Characterization,
Antioxidant Properties and Solid-Phase Peptide Synthesis”
J.Yang et al., - Chemistry, 2007, 13(9): 2530-2545

2. “ The Use of Fullerene Substituted Phenylalanine Amino Acids as a Passport for Peptides through Cell Membranes “
J.Yang et al., - Org.Biomol.Chem., 2007 Jan. 21, 5(2): 260-266

3. “ Human Immunodeficiency Virus-Reserve Transcriptase Inhibition and Hepatitis C Virus RNA-dependent RNA Polymerase Inhibition Activities of Fullerene Derivatives “
T.Mashino et al., - Bioorg.Med.Chem.Lett. 2005 Feb. 15, 15(4): 1107-1109

4. “ Synthesis and Biological Properties of Fullerene-containing Amino Acids and Peptides “
D.Pantarotto et al., - Mini Rev.Med.Chem., 2004 Sep., 4(7): 805-814

5. “ HIV Reproduction Inhibition by Amino Acid and Dipeptide Derivatives of Fullerene C60 “
G.G.Miler et al., - Antibiot. Khimioter., 2004, 49(12): 3-8

6. “ Enantiomers of the Amino Acid Derivatives of Fullerene C60 possess Stereospecific Membranotropic Properties “
G.N.Bogdanov et al., - Dokl.Biochem.Biophys. 2004 May-June, 396: 165-167

7. “ In Vitro Antiviral Activity of Fullerene Amino Acid Derivatives in Cytomegalovirus Infection “
M.G.Medzhidova et al., - Antibit.Khimioter., 2004, 49(8-9): 13-20

8. “ Suppression of Cytomegalovirus Infection in Cell System by Fullerene Amino Acid Derivatives “
N.E.Fedorova et al., - Vopr.Virusol., 2002 Jan-Feb., 47(1): 30-34

9. “ FULLERENE-based AMINO ACIDS and PEPTIDES “
A.Bianco et al., - J.Pept.Sci., 2001 Apr., 7(4): 208-219



LIMITED-TIME OFFER

HIGH-PURIFIED SOLVENT FREE C60 99.95+% - 99.99+%

Fullerenes C60 global demand has been on the rise due to it being one of the best and most powerful antioxidants in the world, proven to have antiviral, anti-aging, immunomodulatory, and antitumor strong effects. Click here for reference.

To help our customers during these unprecedented and turbulent times. MTR Ltd. is offering the best promotion of the year on our High-Purified C60 products:

  • Receive up to 15% off
    your qualifying C60 order of 1-10 grams. Click here to see the price list.
  • Fast worldwide delivery from stock, with FREE Shipping by Express Mail within U.S.
  • Act Fast! Contact Us today for a Quote/Order

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